Everton impressive unbeaten run was cut short by Southampton thanks to two first half goals.
In the 27th minute, James Ward-Prowse was in target for the opener as Che Adams doubled it 8 minutes later thanks to a deflection from Everton.
The visitors who already have 13 points from the competition were without the services of their captain Coleman who is sidelined due to an injury.
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Southampton goalkeeper McCarthy stood untested in the clash after Sigurdsson long range strike hit the goal post for a rebound.
The win also marks exactly one-year since the host suffered a humiliating 9-0 defeat against Leicester in what was thought the end of their Austian coach Ralph Hasenhuttl.
They however believed in him and under his leadership they managed to beat Manchester City, Tottenham and Chelsea earning him his fourth contract with the Saints.
Everton who are confident day in day out were reduced to 10 men after defender Digne following a straight red card in the 72nd minute of the clash.
The results however leave Everton in pole position with 13 points as Southampton settled for 5th position with 10 points.